General Cell Lines and Cell Cultures
Thermo Scientific™ GeneBLAzer™ RARα-UAS-bla HEK 293T Cells
RAR alpha-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human retinoic acid receptor alpha fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK293T cell line.
Thermo Scientific™ CellSensor™ NFkB-bla ME-180 Cell Line
The CellSensor™ NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably integrated into ME-180 cells.
Thermo Scientific™ Tango™ CXCR7-bla U2OS Cells
The Tango™ CXCR7-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 7 (CXCR7) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ NFAT-bla Jurkat Cell Line
The CellSensor™ NFAT-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably integrated into Jurkat cells.
Thermo Scientific™ Tango™ EDG6-bla U2OS Cells
The Tango™ EDG6-bla U2OS cells contain the human Endothelial Differentiation, Lysophosphatidic Acid G-protein-coupled Receptor, 6 (EDG6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ SSTR5-bla U2OS Cells
The Tango™ SSTR5-bla U2OS cells contain the human Somatostatin Receptor 5 (SSTR5) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ CMKLR1-bla U2OS Cells
The Tango™ CMKLR1-bla U2OS cells contain the human Chemokine like receptor 1 (CMKLR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ SBE-bla HEK 293T Cell Line
Smad cell signaling is a critical pathway involved in cell growth and proliferation.
Thermo Scientific™ Tango™ SSTR1-bla U2OS Cells
The Tango™ SSTR1-bla U2OS cells contain the human Somatostatin Receptor 1 (SSTR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ CellSensor™ T-REx™ FOXO3 DBE-bla HeLa Cell Line
The CellSensor™ T-REx™ FOXO3 DBE-bla HeLa cell line was engineered by lentiviral transduction of HeLa cervical cancer cells with a FOXO3 response element driving beta-lactamase expression, along with a tetracycline repressor and tetracycline (or the tetracycline analog doxycycline)-inducible FOXO3 constructs.
Thermo Scientific™ Tango™ AGTR1-bla U2OS Cells
Tango™ AGTR1-bla U2OS cells contain the human Angiotensin Receptor 1 (AGTR1) (AGTR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ PDCD4 HEK 293E Cell Line
The PI3K/AKT/mTOR pathway mediates signals for cell growth and survival, transcription and translation, and regulated cell death.
Thermo Scientific™ GeneBLAzer™ M3-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M3-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ M1-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M1-NFAT-bla CHO-K1 cells contain the human Acetylcholine (muscarinic) subtype 1 receptor (M1) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.